Catalog Number - 68508-10P-4

Cogent RP C8™ HPLC Columns are designed for reliable reversed-phase chromatography using a traditional octyl (C8) bonded stationary phase. Manufactured with ultra-high purity silica and fully double end capped bonding technology, these columns provide reproducible retention, excellent peak shape, and long column life. The RP C8™ phase is a USP L7 equivalent chemistry and is commonly used as an alternative for methods developed on similar C8 phases. Compared to C18 columns, RP C8™ generally provides lower hydrophobic retention while maintaining excellent selectivity for many neutral and non-polar compounds.

68508-10P-4 is packed with 5 µm RP C8™ particles featuring a 100 Å pore size in a 4.0 mm ID x 100 mm length format. The 100 mm column length provides greater resolving power than a 50 mm column while maintaining efficient run times and moderate solvent consumption. The RP C8™ stationary phase is particularly useful for hydrophobic compounds, neutral analytes, and long-chain fatty acids where somewhat lower retention than a comparable C18 column is preferred. The 5 µm particle size provides low backpressure and dependable performance across a wide range of analytical HPLC systems.

The 4.0 mm ID format offers an effective balance between sensitivity, solvent consumption, and compatibility with conventional HPLC instrumentation. This column configuration is ideal for analytical method development, routine quality control testing, and applications where improved resolution is needed without substantially increasing analysis time.

Key Benefits

• RP C8™ stationary phase

• USP L7 equivalent chemistry

• Octyl (C8) bonded phase

• Fully double end capped

• Ultra-high purity silica support

• 100 Å pore size

• Improved resolution compared to 50 mm columns

• Lower retention than C18 phases

• Low backpressure with 5 µm particles

• Compatible with standard HPLC systems

Typical Applications

• Reversed-phase HPLC

• Method development

• Pharmaceutical analysis

• Long-chain fatty acid analysis

• Hydrophobic compound separations

• Neutral compound analysis

• Environmental testing

• Food and beverage analysis

• Quality control testing

• Routine analytical separations

Specifications

• Product Type: HPLC Column

• Stationary Phase: RP C8™

• USP Classification: L7

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double End Capped

• Particle Size: 5 µm

• Pore Size: 100 Å

• Column Dimensions: 4.0 mm ID x 100 mm

• Recommended Flow Rate: 0.8-1.5 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Special Order Item Information

• Please review the Special Order Item Information for complete details.

• For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.

Important Notes

• Designed for reversed-phase HPLC separations requiring improved analytical resolution

• Provides lower retention than comparable C18 columns

• Suitable for hydrophobic and moderately non-polar compounds

• Excellent choice for long-chain fatty acid separations

• 100 mm length provides greater resolving power than shorter analytical columns

• 5 µm particles provide low backpressure and broad instrument compatibility

• Compatible with standard HPLC systems operating at conventional analytical flow rates

• Frequently selected for method development and routine quality control testing

• Manufactured using ultra-high purity silica and fully double end capped bonding technology

• This is a Special Order Item